Cardiobacterium hominis is a slow-growing, fastidious, capnophilic, Gram- negative bacillus represented by the “C” in HACEK, an acronym for. Cardiobacterium hominis is a member of the HACEK group (Haemophilus paraphrophilus, Haemophilus parainfluenzae, Aggregatibacter. Cardiobacterium hominis, a microaerophilic, pleomorphic gram-negative bacillus , is one of the AACEK organisms. C. hominis is a component of the normal flora.

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In one recent report, the organism was recovered only after terminal subculture following 10 days incubation of a BACTEC 6A blood culture bottle With further incubation C. Ruptured mycotic aneurysm of the superior mesenteric artery that was due to Cardiobacterim endocarditis. Report of four cases. Embolism has been responsible for atypical presentations of C hominis endocarditis.

Cardiobacterium hominis endocarditis: two cases and a review of the literature

J Med Microbiol ;3: Cardiobacterium hominis is a member of the normal upper respiratory flora in humans and may be found rarely on other mucosal surfaces. These recommendations are necessarily made on the basis of scanty published data.

Clin Micro Rev ; There are few precedents for managing infection due to isolates resistant to penicillins or cephalosporins, or for treating patients unable to tolerate these antibiotics. Carbapenems were the most active of all the agents tested.


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Five days prior to admission, the patient underwent a colonoscopy. Can Med Assoc J.

Am Surg ; In three patients, blood cultures yielded no organisms, but a definite diagnosis of endocarditis was established by culture of the valve at surgery [ 42 ] or by PCR genome amplification on either the resected valve [ 32 ] or an arterial embolus [ 49 ].

Endocarditis was present in 60 of the 63 reported cases of C. Other antimicrobial agents included fluoroquinolone one casegentamicin, rifampin, and vancomycin. Over the next 5 days, she experienced fever ranging from Endocarditis caused caridobacterium Cardiobacterium hominis — two case reports. Endocarditis caused by Cardiobacterium hominis. However, because of reports of beta-lactamase-producing C. Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account.

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Intracranial mycotic aneurysm in a patient with endocarditis caused by Cardiobacterium hominis. Table 4 Treatment of C.

Regimens recommended to prevent viridans streptococcal endocarditis are generally likely to be effective. Get free access to newly published articles. Han XY, Falsen E. Antonie Van Leeuwenhoek ; Previous valve replacement, previous rheumatic heart disease, previous endocarditis, known ventricular septal defect, known bicuspid aortic valve, congenital aortic valve disease type not specifiedmitral valve prolapse with murmur type not specified and dilated cardiomyopathy have all been described as potential predisposing cardiac lesions in cases of C hominis endocarditis 2 – Cultures taken from the removed porcine valve yielded no growth.


J Infect ; Report of one case and review of the literature. No vertebral biopsies were done. Am Surg ; The majority of C hominis isolates previously reported in the literature were sensitive to penicillin 125 – 911 – 1418192122242528 Currie et al have reviewed 10 cases cardiobafterium C.

Nonsurgical management of mitral valve endocarditis due to Cardiobacterium valvarum in a patient with a ventricular septal defect. Can Assoc Radiol J ; The outcome, with appropriate treatment, is generally good: Case 2 A year-old man with diabetes mellitus underwent porcine aortic valve replacement and coronary artery bypass graft surgery in Anaplasma phagocytophilum Human granulocytic anaplasmosisAnaplasmosis Ehrlichia chaffeensis Human monocytotropic ehrlichiosis Ehrlichia ewingii Ehrlichiosis ewingii infection.